Three-dimensional power Doppler ultrasound image showing the vasculature within and around a transgenic mouse prostate tumour. The bright yellow and darker orange colours correspond to regions containing higher and lower concentrations of moving blood cells, respectively. The tumour is outlined by capsular vessels (arrows) surrounding its perimeter, which are usually well defined in the power Doppler images. See Ultrasound Micro-Imaging of Tumour Progression in Mouse Cancer Models in the Research Interests section for further discussion.

High-frequency ultrasound images of the hearts of newborn wildtype and EphA3-knockout mice. Cross sections through the left atrium (LA), left ventricle (LV), right ventricle (RV), and aortic outflow tract (Ao) are visible in each image. The more circular cardiac cross section of the EphA3-knockout mouse illustrates the dilation of the left atrium observed in this model. See Analysis of Cardiac Valve Function in Neonatal Mice Using High-Frequency Ultrasound in the Research Interests section for further discussion.

Volume rendered high-frequency ultrasound image of a portion of a porcine aortic valve cusp. The rippling of the cusp surface produced by the collagen fibers in the fibrosa is clearly visualized. The three histological layers are readily distinguished because the fibrous outer layers appear hyperechoic (bright) and the aqueous inner layer appears hypoechoic (dark) in the images. See Nondestructive Evaluation of Heart Valve Biomaterials Using High-Frequency Ultrasound in the Research Interests section for further discussion.

Needle positioning robot and high-frequency probe for image guided injections into small animals. The robot includes a rotational axis (A) for adjusting the pitch orientation of the needle, a four-bar linkage mechanism (B) for adjusting the roll orientation of the needle, and a linear motor (C) for needle insertion. In this photograph, the role of the mouse is played by the lab mascot, Bob the Stuffed Gecko. See Ultrasound-Guided Robotic Needle Positioning System for Small Animal Research Applications in the Research Interests section for further discussion.

Three-dimensional computational breast anatomy model for ultrasound imaging simulations. The model includes a branching network of lactiferous ducts (pink) enclosed by the skin and chest wall (gray mesh). The remainder of the volume is filled with fat lobules surrounded by connective tissue septa (not shown). See Computational Modeling of Ultrasound Breast Cancer Imaging in the Research Interests section for further discussion.