The work of Dr. Brian Rutt is focused on quantitative
measurement of anatomical and functional characteristics
of the vasculature using magnetic resonance imaging
(MRI). He leads an ongoing project involving the development
of improved methods for acquiring and displaying MR
angiograms i.e. images of blood vessels. In conjunction
with clinician collaborators, he is evaluating the usefulness
and diagnostic accuracy of several different types of
MRI for diagnosing and characterizing vascular disease
in vivo. He has also been working on the development
of high-speed MRI techniques which will allow the acquisition
of complete image sets in seconds rather than minutes.
This research is aimed at solving the very real problem
of low patient throughput in clinical MRI departments,
and in addition is aimed at the development of dynamic
scanning methods. In addition, he has been working in
the area of MRI hardware development and specifically
the development of advanced "receiver coils",
which receive the very weak magnetic signals that emanate
from the patient's body, and advanced "gradient
coils" which produce the spatial resolution in
MR images. These coil developments are aimed at improving
image quality by improved design of coils and by custom
fitting of coils to patient anatomy.
Key Questions
- Can non-invasive imaging methods identify vulnerable
atherosclerotic plaque?
- Can non-invasive imaging methods identify viable
brain tissue following a stroke?
Selected Publications
- Chronik BA, Rutt BK. "Constrained
Length Minimum Inductance Gradient Coil Design."
Magnetic Resonance in Medicine, 39:270-278,
1998 (PMID: 9469710).
- DeMarco, JK, Rutt BK, Clarke
SE. "Carotid plaque characterization by MR
imaging: Review of the Literature." Topics
in Magnetic Resonance Imaging, 12(3):205-217,
2001 (PMID: 11432578).
- Bowen CV, Zhang X, Saab G, Gareau PJ, Rutt
BK. "Application of the static dephasing
regime theory to superparamagnetic iron-oxide loaded
cells." Magn Reson Med. 2002 Jul;48(1):52-61.
(PMID: 12111931).
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