Dr. Daniel G. Hackam Recent Publications

Book/Monograph

  1. Hackam DG. Building a bridge between animal studies and human randomized trials. 2006. Library and Archives Canada: Published Heritage Branch. ISBN 978-0-494-21893-8. Ottawa, Canada: 2006, Principal Author
  2. Hackam D.G., Anand S.S. Yusuf S. Oral Anticoagulant Therapy in Patients with Coronary Artery Disease. Seminars in Vascular Medicine. 2003, 3. (3): p.323-332, Principal Author

Articles in Refereed Journals

  1. Pike D, Kirby M, Lindenmaier TJ, Sheikh K, Neron CE, Hackam DG, Spence JD, Fenster A, Paterson NA, Sin DD, Coxson HO, McCormack DG, Parraga G. Pulmonary Abnormalities and Carotid Atherosclerosis in Ex-Smokers without Airflow Limitation. 2014 June 12 [Epub ahead of print]. Trainee Publication, Collaborator
  2. Chrysi Bogiatzi, Thapat Wannarong, A. Ian McLeod, Marnin Heisel, Daniel Hackam, David Spence. SPARKLE (Subtypes of Ischaemic Stroke Classification System), Incorporating Measurement of Carotid Plaque Burden: A New Validated Tool for the Classification of Ischemic Stroke Subtypes. Neuroepidemiology, 2014 May 24; 42 (4): 243. Trainee Publication, Collaborator
  3. Elbarasi EA, Goodman SG, Yan RT, Tan MK, Hackam DG, Leiter LA, Langer A, Yan AT; Guidelines Oriented Approach in Lipid Lowering (GOALL) Registry and Vascular Protection (VP) Registry Investigators. Management of risk factors among ambulatory patients at high cardiovascular risk in Canada: a follow-up study. Canadian Journal of Cardiology, 2013 Sep 12; 29 (12): 1586-1592. Trainee Publication, Collaborator
  4. Henderson VC, Kimmelman J, Fergusson D, Grimshaw JM, Hackam DG. Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments. doi: 10.1371/journal.pmed.1001489. Epub 2013 Jul 23. Trainee Publication, Collaborator
  5. Lam NN, Weir MA, Yao Z, Blake PG, Beyea MM, Gomes T, Gandhi S, Mamdani M, Wald R, Parikh CR, Hackam DG, Garg AX. Risk of acute kidney injury from oral acyclovir: a population-based study. Am J Kidney Dis. 2013 May 1; 61 (5): 723-9, Collaborator
  6. Robert R. Quinn, Luc Poirier, Kaberi Dasgupta, Doreen M. Rabi, Daniel G. Hackam, Pietro Ravani, Nadia Khan, Robert J. Herman, Simon Bacon, Ross D. Feldman, Sheldon Tobe, Raj Padwal. 2013 Canadian Hypertension Education Program (CHEP) Recommendations: Scientific Summary. Canadian Journal of Cardiology 2013, Collaborator, Available from: http://www.onlinecjc.ca/article/S0828-282X%2813%2900026-3/fulltext
  7. Hackam DG, Quinn RR, Ravani P, Rabi DM, Dasgupta K, Daskalopoulou SS, Khan NA, Herman RJ, Bacon SL, Cloutier L, Dawes M, Rabkin SW, Gilbert RE, Ruzicka M, McKay DW, Campbell TS, Grover S, Honos G, Schiffrin EL, Bolli P, Wilson TW, Feldman RD, Lindsay P, Hill MD, Gelfer M, Burns KD, Vallée M, Prasad GV, Lebel M, McLean D, Arnold JM, Moe GW, Howlett JG, Boulanger JM, Larochelle P, Leiter LA, Jones C, Ogilvie RI, Woo V, Kaczorowski J, Trudeau L, Petrella RJ, Milot A, Stone JA, Drouin D, Lavoie KL, Lamarre-Cliche M, Godwin M, Tremblay G, Hamet P, Fodor G, Carruthers SG, Pylypchuk GB, Burgess E, Lewanczuk R, Dresser GK, Penner SB, Hegele RA, McFarlane PA, Sharma M, Reid DJ, Tobe SW, Poirier L, Padwal RS; Canadian Hypertension Education Program. The 2013 Canadian Hypertension Education Program (CHEP) Recommendations for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension. Can J Cardiol. 2013 Mar 28. doi:pii: S0828-282X(13)00026-3. 10.1016/j.c, Principal Author
  8. Thapat Wannarong, MD, Grace Parraga, PhD, Daniel Buchanan, MSc, Aaron Fenster, PhD, Andrew A. House, MD, Daniel G. Hackam, MD, PhD and J. David Spence, MD; Progression of Carotid Plaque Volume Predicts Cardiovascular Events. Stroke 2013 Apr 1.
  9. Daniel G Hackam, Marko Mrkobrada. Selective serotonin uptake inhibitors and brain hemorrhage: a meta-analysis. Neurology. 2012;79(18):1862-1865. Principal Author
  10. James J. DiNicolantonio, Pietro Di Pasquale, Rod S. Taylor, Daniel G Hackam. Low sodium versus normal sodium diets in systolic heart failure: systematic review and meta-analysis. Heart. 2012 Aug 21. [Epub ahead of print]
    Senior Responsible Author
  11. Manav V Vyas, Amit X Garg, Arthur V Iansavichus, John Costella, Allan Donner, Lars E Laugsand MD, Imre Janszky MD PhD, Marko Mrkobrada, Grace Parraga PhD, Daniel G Hackam. Shift work and vascular events: systematic review and meta-analysis. BMJ. 2012 Jul 26;345:e4800. doi: 10.1136/bmj.e4800. Trainee Publication, Senior Responsible Author
  12. Gryn SE, Hackam DG; Lifetime Risk Prediction in Cardiovascular Prevention: Wave of the Future? Can J Cardiol. 2012 Jul 6. [Epub ahead of print] No abstract available.
    PMID: 22771015 [PubMed - as supplied by publisher]
  13. Omar de Rita, Daniel G. Hackam, J. David Spence. Effects of aldosterone on human atherosclerosis: plasma aldosterone and progression of carotid plaque. Can J Cardiol. 2012 Jun 19. [Epub ahead of print]. Trainee Publication, Collaborator
  14. Daskalopoulou SS, Khan NA, Quinn RR, Ruzicka M, McKay DW, Hackam DG, Rabkin SW, Rabi DM, Gilbert RE, Padwal RS, Dawes M, Touyz RM, Campbell TS, Cloutier L, Grover S, Honos G, Herman RJ, Schiffrin EL, Bolli P, Wilson T, Feldman RD, Lindsay MP, Hemmelgarn BR, Hill MD, Gelfer M, Burns KD, Vallée M, Prasad GV, Lebel M, McLean D, Arnold JM, Moe GW, Howlett JG, Boulanger JM, Larochelle P, Leiter LA, Jones C, Ogilvie RI, Woo V, Kaczorowski J, Trudeau L, Bacon SL, Petrella RJ, Milot A, Stone JA, Drouin D, Lamarre-Cliché M, Godwin M, Tremblay G, Hamet P, Fodor G, Carruthers SG, Pylypchuk G, Burgess E, Lewanczuk R, Dresser GK, Penner B, Hegele RA, McFarlane PA, Sharma M, Campbell NR, Reid D, Poirier L, Tobe SW; Canadian Hypertension Education Program.The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol. 2012 May;28 (3):270-87. doi: 10.1016/j.cjca.2012.02.018. Review.
    PMID: 22595447 [PubMed - indexed for MEDLINE]
  15. Daniel Buchanan, Tamas Lindenmaier, Shayna Mckay, Yves Bureau, Daniel G Hackam, Aaron Fenster, Grace E Parraga. The relationship of carotid three-dimensional ultrasound vessel wall volume with age and sex: comparison to carotid intima-media thickness. Ultrasound Med Biol. published online May 12, 2012 before print; doi:10.1016/j.ultrasmedbio.2012.02.013. Trainee Publication, Collaborator
  16. Zhao Y, Weir M, Manno M, Cordy P, Gomes T, Hackam DG, Juurlink DN, Mamdani M, Moist L, Parikh P, Paterson JM, Wald R, Garg AX. Acute Renal Events Associated With Fibrate Use in Elderly Patients: A Population-Based Study. Ann Intern Med. 2012 Apr 17;156(8):560-9. Trainee Publication, Collaborator
  17. Bajaj RR, Wald R, Hackam DG, Gomes T, Perl J, Juurlink DN, Manno M, Garg AX, Kitchlu A, Mamdani MM, Yan AT. Use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and cardiovascular outcomes in chronic dialysis patients: a population-based cohort study. Arch Intern Med. 2012 Apr 9;172(7):591-3. Trainee Publication, Collaborator
  18. DiNicolantonio JJ, Hackam DG; Carvedilol: a third-generation β-blocker should be a first-choice β-blocker. Expert Review in Cardiovasc Ther. 2011 Dec 12; 10 (1): 13-25, Senior Responsible Author.
  19. Hackam DG, Woodward M, Newby LK, Bhatt DL, Shao M, Smith EE, Donner A, Mamdani M, Douketis JD, Arima H, Chalmers J, MacMahon S, Tirschwell DL, Psaty BM, Bushnell CD, Aguilar MI, Capampangan DJ, Werring DJ, De Rango P, Viswanathan A, Danchin N, Cheng CL, Yang YH, Verdel BM, Lai MS, Kennedy J, Uchiyama S, Yamaguchi T, Ikeda Y, Mrkobrada M; Statins and intracerebral hemorrhage: collaborative systematic review and meta-analysis. Circulation. Circulation, 2011 Oct 16; 124 (20): 2233-42, Principal Author
  20. Hackam DG, Austin PC, Huang A, Juurlink DN, Mamdani MM, Paterson JM, Hachinski V, Li P, Kapral MK; Statins and intracerebral hemorrhage: a retrospective cohort study. Arch Neurol. 2012 Jan;69(1):39-45. doi: 10.1001/archneurol.2011.228. Epub 2011 Sep 12.
    PMID: 21911657 [PubMed - indexed for MEDLINE]
  21. Kitchlu A, Clemens K, Gomes T, Hackam DG, Juurlink DN, Mamdani M, Manno M, Oliver MJ, Quinn RR, Suri RS, Wald R, Yan AT, Garg AX; Beta-blockers and cardiovascular outcomes in dialysis patients: a cohort study in Ontario, Canada. Nephrol Dial Transplant. 2011 Aug 26. doi: 10.1093/ndt/gfr460. Trainee Publication, Collaborator
  22. Rabi DM, Daskalopoulou SS, Padwal RS, Khan NA, Grover SA, Hackam DG, Myers MG, McKay DW, Quinn RR, Hemmelgarn BR, Cloutier L, Bolli P, Hill MD, Wilson T, Penner B, Burgess E, Lamarre-Cliché M, McLean D, Schiffrin EL, Honos G, Mann K, Tremblay G, Milot A, Chockalingam A, Rabkin SW, Dawes M, Touyz RM, Burns KD, Ruzicka M, Campbell NR, Vallée M, Prasad GV, Lebel M, Campbell TS, Lindsay MP, Herman RJ, Larochelle P, Feldman RD, Arnold JM, Moe GW, Howlett JG, Trudeau L, Bacon SL, Petrella RJ, Lewanczuk R, Stone JA, Drouin D, Boulanger JM, Sharma M, Hamet P, Fodor G, Dresser GK, Carruthers SG, Pylypchuk G, Gilbert RE, Leiter LA, Jones C, Ogilvie RI, Woo V, McFarlane PA, Hegele RA, Poirier L, Tobe SW; Canadian Hypertension Education Program; The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol. 2011 Jul-Aug;27(4):415-433.e1-2. doi: 10.1016/j.cjca.2011.03.015. English, French.
    PMID: 21801975 [PubMed - indexed for MEDLINE]
  23. Hackam DG, Shojania KG, Spence JD, Alter DA, Beanlands RS, Dresser GK, Goela A, Davies AH, Badano LP, Poldermans D, Boersma E, Njike VY; Influence of noninvasive cardiovascular imaging in primary prevention: systematic review and meta-analysis of randomized trials. Arch Intern Med. 2011 Mar 14; 171 (11): 977-82, Principal Author
  24. Vlasschaert ME, Bejaimal SA, Hackam DG, Quinn R, Cuerden MS, Oliver MJ, Iansavichus A, Sultan N, Mills A, Garg AX; Validity of administrative database coding for kidney disease: a systematic review. Am J Kidney Dis. 2010 Dec 29; 57 (1): 29-43. Trainee Publication, Collaborator
  25. Hackam DG, Wu F, Li P, Austin PC, Tobe SW, Mamdani M, Garg AX. Statins and Renovascular Disease in the Elderly: A Population-Based Cohort Study. European Heart Journal 2010 Dec 14; 32 (5): 598-610, Principal Author
  26. Hackam DG, Wu F, Li P, Austin PC, Tobe SW, Mamdani MM, Garg AX; Statins and renovascular disease in the elderly: a population-based cohort study. Eur Heart J. Mar, 2010 Dec 14; 32 (5): 598-610, Principal Author
  27. Hasan K, Lazo-Langner A, Acedillo R, Zeller M, Hackam DG; Anticoagulant response after dalteparin overdose. J Thromb Haemost. 2010 Oct;8(10):2321-3. doi: 10.1111/j.1538-7836.2010.03984.x. No abstract available.
    PMID: 20629941 [PubMed - indexed for MEDLINE]
  28. Lam N, Weir MA, Juurlink DN, Gunraj N, Gomes T, Mamdani M, Hackam DG, Jain AK, Garg AX; Hospital admissions for hyperkalemia with trimethoprim-sulfamethoxazole: a cohort study using health care database codes for 393,039 older women with urinary tract infections. Am J Kidney Dis. 2010 Sept 2; 26 (6): 1888-94. Trainee Publication, Collaborator
  29. Weir MA, Gomes T, Mamdani M, Juurlink DN, Hackam DG, Mahon JL, Jain AK, Garg AX; Impaired renal function modifies the risk of severe hypoglycaemia among users of insulin but not glyburide: a population-based nested case-control study. Nephrol Dial Transplant. 2010 Sep 2; 26 (6): 1888-94. Trainee Publication, Collaborator
  30. J. David Spence and Daniel G. Hackam; Treating Arteries Instead of Risk Factors. A Paradigm Change in Management of Atherosclerosis; Stroke 2010, April 22; 41 (6): 1193-9, Co-Principal Author
  31. Spence JD, Coates V, Li H, Tamayo A, Munoz C, Hackam DG, DiCicco M, DesRoches J, Bogiatzi C, Klein J, Madrenas J, Hegele RA. Intensive medical therapy reduces microemboli and cardiovascular risk in asymptomatic carotid stenosis. Archives of Neurology, 2010 Jan 1; 67 (2): 180-186, Collaborator
  32. Lam N, Jain AK, Hackam DG, Cuerden MS, Suri RS, Huo C, Li P, Clark WF, Garg AX. Impact of a Randomized Controlled Trial on Statin Use in Dialysis Patients. Kidney International 2009 Sep 23. [Epub ahead of print], Collaborator
  33. Hackam DG; Kapral MK; Wang J; Fang J; Hachinski V. Most stroke patients do not get a warning. Neurology, 2009 Sep; 73 (13): 1074-6, Principal Author
  34. Hackam DG; Sultan NM; Criqui MH. Vascular Protection in Peripheral Arterial Disease: Systematic Review and Risk Modelling Study. Heart, 2009 Mar 15; 95 (13): 1098-102, Principal Author
  35. Tonelli M, Hackam D, Garg A. Primer on systematic review and meta-analysis. Methods in Molecular Biology 2009;473:217-33, Collaborator
  36. Tsang JLY, Mendelsohn A, Tan MKK, Hackam DG, Leiter LA, Fitchett D, Lin PJ, Grima E, Langer A, Goodman SG, for the Vascular Protection Registry and Guidelines Oriented Approach to Lipid Lowering Registry Investigators. Discordance between physicians’ estimation of patient cardiovascular risk and use of evidence-based medical therapy. American Journal of Cardiology, 2008 Nov 1; 102 (9): 1142-1145, Collaborator
  37. Sankalp Bhavsar, Andre Nimigan, Daniel G. Hackam, David B. O’Gorman, Bing Siang Gan, J David Spence. Keloid scarring, but not Dupuytren’s contracture, is associated with unexplained carotid atherosclerosis. Clinical Investigative Medicine, 2008 Nov; 32 (2): E95-102, Collaborator
  38. Hackam DG, Duong-Hua ML, Muhammad M, Li P, Tobe SW, Spence JD, Garg AX. Angiotensin inhibition in renovascular disease: a population-based cohort study. 2008 Oct 1; 156 (3): 549-55, Principal Author
  39. Klein JH, Hegele RA, Hackam DG, Koschinsky ML, Huff MW, Spence JD. Lipoprotein(a) Is Associated Differentially With Carotid Stenosis, Occlusion, and Total Plaque Area. Arteriosclerosis Thrombosis & Vascular Biology 2008; 28:1851-1856, Collaborator
  40. Hackam D.G., Hackam A.S. Translation of genetic discoveries into clinical therapies. Annals of Internal Medicine. 2008 Feb 1; 148 (3): 246-7; Principal Author
  41. Garg A.X., Hackam D., Tonelli M. Systematic review and meta-analysis: when one study is just not enough. Clinical Journal of the American Society of Nephrology 2008 Jan;3(1):253-60. Collaborator
  42. Hackam D.G. The ankle brachial index independently predicted all-cause mortality in high-risk patients with peripheral arterial disease. Evidence-Based Medicine 2007 Dec;12(6):187.
  43. Hackam D.G., Leiter L.A., Yan A.T., Yan R.T., Mendelsohn A., Tan M., Zavodni L., Chen R., Tsang J.L., Kundi A., Lin P.J., Fitchett D.H., Langer A., Goodman S.G.; Vascular Protection Registry and Guideline Oriented Appraoch to Lipid Lowering Registry Investigators. Missed opportunities for the secondary prevention of cardiovascular disease in Canada. Canadian Journal of Cardiology 2007 Dec;23(14):1124-30. Principal Author
  44. Hackam D.G. The ankle-brachial index independently predicted all-cause mortality in high-risk patients with peripheral arterial disease. American College of Physicians Journal Club 2007 Nov-Dec;147(3):81.
  45. Hackam D.G., Spence J.D., Garg A.X., Textor S.C. Role of renin-angiotensin system blockade in atherosclerotic renal artery stenosis and renovascular hypertension. Hypertension. 2007 Dec;50(6):998-1003, Principle Author
  46. Avner M., Finkelstein Y., Hackam D., Koren G. Establishing causality in pediatric adverse drug reactions : use of the naranjo probability scale. Paediatric Drugs 2007 Aug 1; 9 (4): 267-270, Collaborator
  47. Hackam D.G. Predicting stroke risk in patients with atrial fibrillation. Stroke 2007;38:2409.
  48. Hackam D.G. Review: antioxidant supplements for primary and secondary prevention do not decrease mortality. American College of Physicians Journal Club 2007;147:4.
  49. Terblanche M., Almog Y., Rosenson R.S., Smith T.S., Hackam D.G. Statins and sepsis: multiple modifications at multiple levels. Lancet Infect Dis. 2007;7:358-368.
  50. Hackam D.G., Spence J.D. Combining multiple approaches for the secondary prevention of vascular events after stroke: a quantitative modeling study. Stroke. 2007 Jun 1; 38 (6): 1881-5, Principal Author
  51. Hackam DG, Eikelboom JW. Antithrombotic Therapy for Peripheral Arterial Disease. Heart, 2007 May 1; 93 (3): 303-8, Principal Author
  52. Hackam D.G. Translating animal research into clinical benefit. British Medical Journal 2007;334:163-164.
  53. Hackam D.G., Eikelboom J.W. Antithrombotic treatment for peripheral arterial disease. Heart. 2007;93:303-308.
  54. Hackam D.G. Intensive reduction of low-density lipoprotein-cholesterol: implications of recent trials. American Journal of Cardiovascular Drugs. 2006;6:367-371.
  55. Hackam D.G., Redelmeier D.A. Translating Evidence from Animals to Humans: A Systematic Review. JAMA, 2006 Oct 15; 296 (14): 1731-2;, Principal Author
  56. Hackam D.G., Tan MK, Lin PJ, Mehta PG, Jaffer S, Kates M, Oh M, Grima EA, Langer A, Goodman SG; Vascular Protection Registry; Guideline Oriented Approach in Lipid Lowering Registry Investigators. Supporting a Call to Action for Peripheral Artery Disease: Insights from Two Prospective Clinical Registries. Journal of Vascular Surgery, 2006 Aug 22; 44 (4): 776-81, Principal Author
  57. Hackam D.G., Thiruchelvam D., Redelmeier D.A.. Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study. Lancet. 2006 Aug 15; 368 (9536): 659-65, Principal Author
  58. Yan A, Yan R, Tan M, Hackam DG, Leblanc KL, Kertland H, Tsang JL, Jaffer S, Kates ML, Leiter LA, Fitchett DH, Langer A, Goodman SG for the Vascular Protection Registry and Guidelines Oriented Approach to Lipid Lowering Registry Investigators. Contemporary Management of Dyslipidemia in High-risk Patients: Targets Still Not Met. American Journal of Medicine. 2006 Aug 1; 119 (8): 676-683, Collaborator
  59. Hackam D.G. Medical management of peripheral arterial disease. Journal of the American Medical Association. 2006;296:41-42.
  60. Terblanche M., Almog Y., Rosenson R.S., Smith T.S., Hackam D.G. Statins: panacea for sepsis? Lancet Infectious Diseases. 2006 Mar 1; 6 (4): 242-248, Collaborator
  61. Hackam D.G. Perioperative beta-blocker therapy in vascular surgery: clinical update. Journal of Vascular Surgery. 2006 Mar 1; 43 (3): 629-631, Principal Author
  62. Hackam D.G., Mamdani M., Li P., Redelmeier D.A. Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis. Lancet. 2006 Feb 1; 367 (9508): 413-8, Principal Author
  63. Hackam D.G. Intensive Reduction of Low Density Lipoprotein Cholesterol: Implications of Recent Trials. American Journal of Cardiovascular Drugs, 2006; 6 (6): 367-71, Principal Author
  64. Hackam D.G., Goodman S.G, Anand S.S. Management of risk in peripheral artery disease: recent therapeutic advances. American Heart Journal. 2005;150 (1):35-40, Principal Author
  65. Hackam D.G., Kopp A. Redelmeier D.A. Prognostic Implications of Warfarin Cessation Following Major Trauma: A Population Based Cohort Analysis. Circulation, 2005; 111 (17): 2250-2256, Principal Author
  66. Hackam D.G. Cardiovascular risk prevention in peripheral artery disease. Journal of Vascular Surgery. 2005;41 (6):1051-1053, Principal Author
  67. Hackam D.G. Does intensified cholesterol lowering provide greater protection from cardiovascular events among patients with stable coronary artery disease? Canadian Medical Association Journal. 2005;172:1294-1295.
  68. Hackam D.G., Kopp A., Redelmeier D.A. Prognostic implications of warfarin cessation after major trauma: a population-based cohort analysis. Circulation. 2005;111:2250-2256.
  69. Hackam D.G., Tan M.K., Honos G.N., Leiter LA., Langer A., Goodman S.G. How does the prognosis of diabetes compare with that of established vascular disease? Insights from the Canadian Vascular Protection (VP) Registry. American Heart Journal. 2004;148:1028-1033, Principal Author
  70. Hackam D.G. The PROGRESS trial three years later: Clear and accurate interpretations of studies are needed. British Medical Journal. 2004;329:1404.
  71. Hackam D.G., Kapral M.K. Progress in clinical neurosciences: pharmacotherapies for the secondary prevention of stroke. Canadian Journal Neurological Sciences. 2004;31 (3):295-303, Principal Author
  72. Hackam D.G., Shumak S.L. C-reactive protein for the prediction of cardiovascular risk: ready for prime-time? Canadian Medical Association Journal. 2004;170:1563-1565, Principal Author
  73. Hackam D.G. Acarbose reduced the risk for cardiovascular disease and hypertension in impaired glucose tolerance. American College of Physicians Journal Club 2004;140:2.
  74. Hackam D.G., Anand S.S., Yusuf S. Oral anticoagulant therapy in patients with coronary artery disease. Seminars in Vascular Medicine. 2003;3:323-332.
  75. Hackam D.G. ACE inhibition in stable coronary artery disease. Canadian Medical Association Journal. 2003;169:939.
  76. Hackam D.G. Aldosterone blockade after myocardial infarction. Canadian Medical Association Journal. 2003;169:444.
  77. Hackam D.G., Anand S.S. Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence. Journal of the American Medical Association. 2003; 290 (7):932-940, Principal Author
  78. Hackam D.G. Extending the Scope of Statins: Recent Clinical Trials. Perspectives in Cardiology 19(6):24-29, Principal Author
  79. Hackam D.G. Do hypertensive patients with average cholesterol levels benefit from atorvastatin therapy? Canadian Medical Association Journal. 2003;168:1689.
  80. Hackam D.G., Anand S.S. Commentary: cardiovascular implications of the epidemiological transition for the developing world: Thailand as a case in point. International Journal of Epidemiology. 2003;32:468-469.
  81. Hackam D.G. Treatment of chronic obstructive pulmonary disease: Combination or component therapy? Canadian Medical Association Journal. 2003;168:1296-1297.
  82. Hackam D.G. Long-term, low-intensity warfarin after idiopathic venous thromboembolism. Canadian Medical Association Journal. 2003;168:1160-1161.
  83. Hackam D.G. Drug treatment of hypertension. Conclusion of editorial is somewhat flawed. British Medical Journal. 2003;326:764.
  84. Hackam D, Anand S.S. Acetylcysteine for prevention of acute deterioration of renal function following elective coronary angiography and intervention: a randomized controlled trial. Vascular Medicine. 2002;7:337-338.
  85. Spence J.D., Eliasziw M., DiCicco M., Hackam D.G., Galil R., Lohmann T. Carotid plaque area: a tool for targeting and evaluating vascular preventive therapy. Stroke. 2002;33:2916-2922, Collaborator
  86. Hackam D.G., Thain L.M., Abassakoor A, McKenzie F.N., Spence J.D. Trapped renal arteries: functional renal artery stenosis due to occlusion of the aorta in the arch and below the kidneys. Canadian Journal of Cardiology. 2001;17:587-592, Principal Author
  87. Hackam D.G., Peterson J.C., Spence J.D. What level of plasma homocyst(e)ine should be treated? Effects of vitamin therapy on progression of carotid atherosclerosis in patients with homocyst(e)ine levels above and below 14 micromol/L. American Journal of Hypertension. 2000;13:105-110, Principal Author
  88. Hackam D.G., Zwimpfer T.J. Congenital entrapment of the lateral cutaneous nerve of the calf presenting as a personal sensory neuropathy. Canadian Journal Neurological Sciences. 1998;25:168-170, Principal Author

Accepted/In Press

  1. Chrysi Bogiatzi, Daniel Hackam, A. Ian McLeod, J. David Spence. Secular Trends in Ischemic Stroke Subtypes and Stroke Risk Factors. 2014; in press. Trainee Publication, Collaborator
  2. Amna N. Ahmed, Ken Blonde, Daniel Hackam, Alla Iansavichene, Marko Mrkobrada. Prognostic Significance of Elevated Troponin in Non-cardiac Medicine Inpatients: A Systematic Review and Meta-analysis. 2014; in press. Trainee Publication, Collaborator

Guideline Article

  1. Daskalopoulou SS, Khan NA, Quinn RR, Ruzicka M, McKay DW, Hackam DG, Rabkin SW, Rabi DM, Gilbert RE, Padwal RS, Dawes M, Touyz RM, Campbell TS, Cloutier L, Grover S, Honos G, Herman RJ, Schiffrin EL, Bolli P, Wilson T, Feldman RD, Lindsay MP, Hemmelgarn BR, Hill MD, Gelfer M, Burns KD, Vallée M, Prasad GV, Lebel M, McLean D, Arnold JM, Moe GW, Howlett JG, Boulanger JM, Larochelle P, Leiter LA, Jones C, Ogilvie RI, Woo V, Kaczorowski J, Trudeau L, Bacon SL, Petrella RJ, Milot A, Stone JA, Drouin D, Lamarre-Cliché M, Godwin M, Tremblay G, Hamet P, Fodor G, Carruthers SG, Pylypchuk G, Burgess E, Lewanczuk R, Dresser GK, Penner B, Hegele RA, McFarlane PA, Sharma M, Campbell NR, Reid D, Poirier L, Tobe SW; Canadian Hypertension Education Program. The 2012 canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol. 2012 May 1, 28. (3): p.270-87, Collaborator
  2. Rabi DM, Daskalopoulou SS, Padwal RS, Khan NA, Grover SA, Hackam DG, Myers MG, McKay DW, Quinn RR, Hemmelgarn BR, Cloutier L, Bolli P, Hill MD, Wilson T, Penner B, Burgess E, Lamarre-Cliche M, McLean D, Schiffrin EL, Honos G, Mann K, Tremblay G, Milot A, Chockalingam A, Rabkin SW, Dawes M, Touyz RM, Burns KD, Ruzicka M, Campbell NR, Vallee M, Prasad GV, Lebel M, Campbell TS, Lindsay MP, Herman RJ, Larochelle P, Feldman RD, Arnold JM, Moe GW, Howlett JG, Trudeau L, Bacon SL, Petrella RJ, Lewanczuk R, Stone JA, Drouin D, Boulanger JM, Sharma M, Hamet P, Fodor G, Dresser GK, Carruthers SG, Pylypchuk G, Gilbert RE, Leiter LA, Jones C, Ogilvie RI, Woo V, McFarlane PA, Hegele RA, Poirier L, Tobe SW; Canadian Hypertension Education Program. The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Canadian Journal of Cardiology. 2011 Aug 2, 27. (4): p.415-433, Collaborator
  3. Hackam DG, Khan N, Hemmelgarn B, Rabkin S, Touyz R, Campbell N, Padwal R, Campbell T, Lindsay M, Hill M, Quinn R, Mahon J, Herman R, Schiffrin E, Ruzicka M, Larochelle P, Feldman R, Lebel M, Poirier L, Arnold J, Moe G, Howlett J, Trudeau L, Bacon S, Petrella R, Milot A, Stone J, Drouin D, Boulanger J, Sharma M, Hamet P, Fodor G, Dresser G, Carruthers S, Pylypchuk G, Burgess E, Burns K, Vallée M, Prasad G, Gilbert R, Leiter L, Jones C, Ogilvie R, Woo V, McFarlane P, Hegele R, Tobe S. The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol. 2010 May 1, 26. (5): p.249-58, Principal Author
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